Just when you think weโ€™ve gotten to the bottom of this whole โ€œcoffee is good for youโ€ thing, a new team of researchers fearlessly plumb the depths even further to find an as-yet-undiscovered cavern of coffee healthfulness. In a new study of nearly 350,000 participants, researchers from the Australian Centre for Precision Health found the number of cups of coffee you can drink per day before the risks outweigh the benefits. That number is five.

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As reported by Inc.com, the new study first appeared in the March 2019 issue of the American Journal for Clinical Nutrition and was made public last week. In it, authors Ang Zhou and Elina Hyppรถnen were looking to discover if a specific genotype, CYP1A2, has any effect on “the association between habitual coffee consumption and the risk of cardiovascular disease (CVD).” For their work, the pair of researchers pored over data on 347,077 individuals in the UK Biobankโ€”including 8,368 people with CVDโ€”to cross-reference their genetic data against their “habitual coffee intake.”

Though their results found no link between the CYP1A2 genotype and an increased risk of CVD, Ang and Hyppรถnen’s work did uncover some interesting correlations. Using those who drank one to two cups of coffee daily as the baseline, the results of the survey were “nonlinear.” They found that those who didn’t drink coffee or only drank decaf were linked with an increase in CVD, by 11% and 7%, respectively. But those who drank six or more cups daily boosted the instances of CVD to 22%, double that of the non-coffee drinkers and triple of the decaf drinkers.

“In order to maintain a healthy heart and a healthy blood pressure, people must limit their coffees to fewer than six cups a day – based on our data six was the tipping point where caffeine started to negatively affect cardiovascular risk,” Hyppรถnen states.

Mark it five, dude. That’s the limit science is putting on the number of cups of coffee you should have a day. For most people, five cups gives a pretty wide berth before running afoul of the scientific limits. For everyone else, though, I’d suggest maybe altering your coffee intake to just one cup daily. The key is finding the right cup.

Zac Cadwaladerย is the managing editor at Sprudge Media Network and a staff writer based in Dallas.ย Read more Zac Cadwaladerย on Sprudge.

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